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J Am Coll Cardiol, 2007; 49:1634-1641, doi:10.1016/j.jacc.2006.12.041 (Published online 30 March 2007).
© 2007 by the American College of Cardiology Foundation
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Pulmonary Vein Antral Isolation Using an Open Irrigation Ablation Catheter for the Treatment of Atrial Fibrillation

A Randomized Pilot Study

Mohamed H. Kanj, MD*, Oussama Wazni, MD*, Tamer Fahmy, MD, PhD*, Sergio Thal, MD*, Dimpi Patel, MD*, Claude Elay, MD*, Luigi Di Biase, MD*,{dagger}, Mauricio Arruda, MD*, Walid Saliba, MD*, Robert A. Schweikert, MD*, Jennifer E. Cummings, MD*, J. David Burkhardt, MD*, David O. Martin, MD*, Gemma Pelargonio, MD{ddagger}, Antonio Dello Russo, MD{ddagger}, Michela Casella, MD{ddagger}, Pietro Santarelli, MD§, Domenico Potenza, MD||, Raffaele Fanelli, MD||, Raimondo Massaro, MD||, Giovanni Forleo, MD|| and Andrea Natale, MD*,*

* Cleveland Clinic, Cleveland, Ohio
{dagger} University of Insubria, Varese, Italy
{ddagger} Catholic University, Rome, Italy
§ Catholic University, Campobasso, Italy
|| Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy.


Figure 1
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  		Figure 1 Power Titration in the 3 Catheter Groups

(A) Open irrigation catheter using higher power (50 W), (B) open irrigation catheter using lower power (35 W), and (C) 8-mm catheter groups. ET = esophageal temperature; ICE = intracardiac echocardiography.

 

Figure 2
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  		Figure 2 Short- and Long-Term Procedural Success

Success was defined as (A) pulmonary vein antrum isolation and (B) freedom of any atrial arrhythmias at 6 months. 8MC = 8-mm catheter; OIC-1 = 3.5-mm open irrigation tip catheter using a higher power and higher irrigation flow rate; OIC-2 = 3.5-mm ThermoCool open irrigation tip catheter using a lower power and lower irrigation flow rate; PVAI = pulmonary vein antrum isolation.

 

Figure 3
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  		Figure 3 Time Intervals

(A) Fluoroscopy time, (B) left atrial (LA) instrumentation time, and (C) ablation along the esophagus time in the 3 study groups. Abbreviations as in Figure 2.

 

Figure 4
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  		Figure 4 Periprocedural Complications

(A) Incidence of pops during ablation, (B) pericardial effusion, (C) pulmonary edema, and (D) gastrointestinal complaints. Abbreviations as in Figure 2.

 

Figure 5
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  		Figure 5 Esophageal Temperature Elevation in the 3 Study Groups

(A) Incidence of ET elevation (%), (B) distribution of ET elevation, (C) postablation rise in ET, (D) time for ET to return to baseline postablation, and (E) postablation ET tracings. RF = radiofrequency; other abbreviations as in Figures 1 and 2.

 




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Copyright © 2007 by the American College of Cardiology Foundation.