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J Am Coll Cardiol, 2007; 49:1546-1551, doi:10.1016/j.jacc.2006.12.039 (Published online 26 March 2007). © 2007 by the American College of Cardiology Foundation

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Rate of Progression of Coronary Atherosclerotic Plaque in Women

Stephen J. Nicholls, MBBS, PhD, FRACP, FACC^_*,,,1,_*, Kathy Wolski, MPH^_*, Ilke Sipahi, MD^_*,3, Paul Schoenhagen, MD^_*,, Timothy Crowe, BS^_*, Samir R. Kapadia, MD, FACC^_*, Stanley L. Hazen, MD, PhD^_*,,,2, E. Murat Tuzcu, MD, FACC^_*,2 and Steven E. Nissen, MD, FACC^_*,4

^_* Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio
Department of Cell Biology, Cleveland Clinic Foundation, Cleveland, Ohio
Center for Cardiovascular Diagnostics and Prevention, Cleveland Clinic Foundation, Cleveland, Ohio
Department of Diagnostic Radiology, Cleveland Clinic Foundation, Cleveland, Ohio.

View larger version (24K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Rate of Progression and Regression With Intensive Risk Factor Modification Percentage of female (solid squares) and male (open squares) subjects who underwent plaque progression (A) or regression (B) with intensive modification of a number of risk factors resulting in low-density lipoprotein (LDL) <80 mg/dl, systolic blood pressure (SBP) <120 mm Hg, or C-reactive protein (CRP) <2 mg/l.