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J Am Coll Cardiol, 2007; 49:1265-1271, doi:10.1016/j.jacc.2007.02.021
© 2007 by the American College of Cardiology Foundation
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Does Addition of Estradiol Improve the Efficacy of a Rapamycin-Eluting Stent?

Results of the ISAR-PEACE Randomized Trial

Tom Adriaenssens, MD, Julinda Mehilli, MD*, Rainer Wessely, MD, Gjin Ndrepepa, MD, Melchior Seyfarth, MD, Anna Wieczorek, Birgit Blaich, PhD, Raisuke Iijima, MD, Jürgen Pache, MD, Adnan Kastrati, MD1 and Albert Schömig, MD2

Deutsches Herzzentrum, Technische Universtität, Munich, Germany.


Figure 1
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Figure 1 Release Kinetics of Rapamycin From the ERES and RES

Kinetics are displayed as cumulative release of rapamycin over time in percent of total rapamycin on the stents (± SD). ERES = estradiol plus rapamycin-eluting stent; RES = rapamycin-eluting stent.

 

Figure 2
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Figure 2 Flow Chart of Study Participants

 

Figure 3
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Figure 3 Cumulative Frequency Curves of In-Stent Late Lumen Loss at Follow-Up Angiography for the 2 DES Groups

DES = drug-eluting stent; other abbreviations as in Figure 1.

 

Figure 4
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Figure 4 Incidences of Angiographic and Clinical Restenosis for the ERES and RES Groups

TLR = target lesion revascularization; other abbreviations as in Figure 1.

 

Figure 5
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Figure 5 Probability of Survival Free of MI for the ERES Group and for the RES Group

MI = myocardial infarction; other abbreviations as in Figure 1.

 




 
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