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J Am Coll Cardiol, 2007; 49:1149-1156, doi:10.1016/j.jacc.2006.12.028 (Published online 5 March 2007).
© 2007 by the American College of Cardiology Foundation
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Impact of Metabolic Syndrome on Tissue Characteristics of Angiographically Mild to Moderate Coronary Lesions

Integrated Backscatter Intravascular Ultrasound Study

Tetsuya Amano, MD, PhD*,*, Tatsuaki Matsubara, MD, PhD{dagger}, Tadayuki Uetani, MD, PhD*, Michio Nanki, MD, PhD*, Nobuyuki Marui, MD, PhD*, Masataka Kato, MD*, Kosuke Arai, MD*, Kiminobu Yokoi, MD*, Hirohiko Ando, MD*, Hideki Ishii, MD{ddagger}, Hideo Izawa, MD, PhD{ddagger} and Toyoaki Murohara, MD, PhD{ddagger}

* Department of Cardiology, Chubu-Rosai Hospital, Nagoya, Japan
{dagger} Department of Internal Medicine, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan
{ddagger} Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.


Figure 1
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  		Figure 1 Representative Images of Conventional Intravascular Ultrasound and 2-Dimensional Integrated Backscatter Intravascular Ultrasound Color-Coded Maps of Coronary Artery Plaques in Patients With or Without MetS

(A) Patients with (+) metabolic syndrome (MetS); (B) patients without (–) MetS. The percentage of lipid area and the percentage of fibrous area were 46.1% and 50.1% in panel A, and 12.1% and 80.9% in panel B, respectively. Blue = lipid pool; green yellow = fibrous lesion; red = high signal lesion.

 

Figure 2
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  		Figure 2 Representative Images of the 3-Dimensional Integrated Backscatter Intravascular Ultrasound in Patients With or Without MetS

(A) Patients with (+) metabolic syndrome (MetS); (B) patients without (–) MetS. The percentage of lipid volume was 52.7% in panel A and 23.0% in panel B. Blue and light blue = lipid pool; green and yellow = fibrous lesion; red = high signal lesion.

 

Figure 3
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  		Figure 3 The Lipid-Rich Plaque Rate According to Increasing Numbers of MetS Components

The lipid-rich plaque rate was significantly associated with an increasing number of metabolic syndrome (MetS) components in the grouping. p = 0.002 by analysis of variance (ANOVA).

 




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Copyright © 2007 by the American College of Cardiology Foundation.