Diagnostic Accuracy of Rubidium-82 Myocardial Perfusion Imaging With Hybrid Positron Emission Tomography/Computed Tomography in the Detection of Coronary Artery Disease
Uchechukwu K. Sampson, MD, MPH, MBA, MSc(Oxon)*,
Sharmila Dorbala, MD, FACC*, ,
Atul Limaye, MD, MRCP*,
Raymond Kwong, MD*, and
Marcelo F. Di Carli, MD, FACC, FAHA*,,*
* Divisions of Nuclear Medicine and Cardiovascular Imaging, Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
Division of Cardiology, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts.
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Figure 1 Normal Rubidium-82 Myocardial Perfusion PET-CT Study
Dipyridamole-stress and rest rubidium-82 positron emission tomography-computed tomography (PET-CT) images in corresponding short-axis (top), vertical long-axis (middle), and horizontal long-axis (bottom) slices in a 55-year-old woman with atypical chest pain (height 5’5", weight 205 lbs, body mass index = 34). The short-axis slices represent progression from the apical (left) to the basal (right) part of the heart, and are oriented with the anterior wall on the top, the lateral wall to the right, the inferior wall at the bottom, and the interventricular septum to the left. The vertical long-axis slices represent progression from the septum (left) to the lateral (right) walls, and are oriented with the anterior wall on top, inferior wall at the bottom, and the left ventricular (LV) apex to the right. The horizontal long-axis slices represent progression from the inferior (left) to the anterior (right) walls, and are oriented with the septal wall on the left, lateral wall to the right, and the LV apex on the top. The images show normal myocardial perfusion throughout the LV and represent a normal scan.
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Figure 2 Abnormal Rubidium-82 Myocardial Perfusion PET-CT Study
Dipyridamole-stress and rest rubidium-82 PET-CT images in corresponding short-axis (top), vertical long-axis (middle), and horizontal long-axis (bottom) slices in a 62-year-old man with atypical chest pain (height 6’0", weight 235 lbs, body mass index = 31.9). The orientation is as in Figure 1. The images are abnormal and consistent with a moderately large area of severe ischemia in the lateral and inferolateral walls (left circumflex territory), and a small area of mild ischemia involving the apical LV segments and the apex (distal left anterior descending territory). Abbreviations as in Figure 1.
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