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Metabolic Syndrome and Early-Onset Coronary Artery Disease

Is the Whole Greater Than Its Parts?

Carlos Iribarren, MD, MPH, PhD^_*,,_*, Alan S. Go, MD^_*,, Gail Husson, MPH, Med^_*, Stephen Sidney, MD, MPH^_*, Joan M. Fair, ANP, PhD, Thomas Quertermous, MD, Mark A. Hlatky, MD^,|| and Stephen P. Fortmann, MD

^_* Kaiser Permanente Division of Research, Oakland, California
Departments of Epidemiology, Biostatistics, and Medicine, University of California, San Francisco, California
Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, California
Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California
^|| Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California

View larger version (14K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Early-onset coronary artery disease (CAD) definition criteria in the ADVANCE Study. CABG = coronary artery bypass graft; CK-MB = creatine kinase-MB fraction; CPT = current procedural terminology; EKG = electrocardiogram; ICD-9 = ninth revision of the International Classification of Diseases; MD = metabolic syndrome; PCI = percutaneous coronary intervention.

View larger version (20K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Schematic representation of the recruitment process for early-onset coronary artery disease subjects in the ADVANCE study. PCP = primary care provider. *Numbers do not add up because electronic exclusions are not mutually exclusive.