Effects of Statin Therapy on Arrhythmic Events and Survival in Patients With Nonischemic Dilated Cardiomyopathy
Jeffrey J. Goldberger, MD, FACC*,*,
Haris Subacius, MA*,
Andi Schaechter, RN*,
Adam Howard, BA*,
Ronald Berger, MD, PhD, FACC
,
Alaa Shalaby, MD, FACC
,
Joseph Levine, MD
,
Alan H. Kadish, MD, FACC* for the DEFINITE Investigators
* Clinical Trials Unit, Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, and the Division of Cardiology, Feinberg School of Medicine, Chicago, Illinois
Johns Hopkins Hospital, Baltimore, Maryland
VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania
Heart Center, St. Francis Hospital, Roslyn, New York.

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Figure 1 The Kaplan-Meier estimates of total mortality plus resuscitated cardiac arrest among patients treated with statins and those not taking statins in the 458 patients enrolled in the DEFINITE trial.
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Figure 2 The Kaplan-Meier estimates of arrhythmic sudden death plus resuscitated cardiac arrest among patients treated with statins and those not taking statins in the 458 patients enrolled in the DEFINITE trial.
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Figure 3 The Kaplan-Meier estimates of appropriate shocks among patients treated with statins and those not taking statins in the 229 patients randomized to ICD therapy in the 458 patients enrolled in the DEFINITE trial.
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Figure 4 Distribution of number of appropriate shocks received per patient in patients treated with statins and those not taking statins.
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Copyright © 2006 by the American College of Cardiology Foundation.