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Corrected QT Variability in Serial Electrocardiograms in Long QT Syndrome

The Importance of the Maximum Corrected QT for Risk Stratification

Ilan Goldenberg, MD^_*,_*, Jehu Mathew, BS^_*, Arthur J. Moss, MD^_*, Scott McNitt, MS^_*, Derick R. Peterson, PhD, Wojciech Zareba, MD, PhD^_*, Jesaia Benhorin, MD, Li Zhang, MD, G. Michael Vincent, MD, FACC^,||, Mark L. Andrews, BBS^_*, Jennifer L. Robinson, MS^_* and Brian Morray, BS^_*

^_* Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York
Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York
Bikur Cholim Hospital, University of Jerusalem, Jerusalem, Israel
Latter Day Saints Hospital, Salt Lake City, Utah
^|| University of Utah School of Medicine, Salt Lake City, Utah.

View larger version (16K): [in a new window]   Figure 1 Kaplan-Meier estimates of the probability of a first cardiac event between ages 10 and 20 years in patients with the following combinations of corrected QT (QTc) measures: maximum QTc <500 ms and baseline QTc <500 ms; maximum QTc 500 ms and baseline QTc <500 ms; and maximum QTc 500 ms and baseline QTc 500 ms.