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J Am Coll Cardiol, 2006; 48:677-685, doi:10.1016/j.jacc.2006.03.052 (Published online 24 July 2006).
© 2006 by the American College of Cardiology Foundation
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The Effects of Diet on Inflammation

Emphasis on the Metabolic Syndrome

Dario Giugliano, MD, PhD*,*, Antonio Ceriello, MD{dagger} and Katherine Esposito, MD, PhD*

* Division of Metabolic Diseases, Center of Excellence for Cardiovascular Diseases, University of Naples SUN, Italy
{dagger} Warwick Medical School, Coventry, United Kingdom


Figure 1
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  		Figure 1 Some mechanisms through which unhealthy dietary patterns may lead to coronary heart disease (CHD). LDL = low-density lipoprotein.

 

Figure 2
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  		Figure 2 Mechanisms through which hyperglycemia may generate inflammatory responses. NF-kB = nuclear factor kappa B; PKC = protein kinase C.

 

Figure 3
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  		Figure 3 Effects of a 2-year dietetic approach with a Mediterranean-style diet in patients with the metabolic syndrome. The number of components of the syndrome was reduced approximately by one-half in the intervention group (100).

 

Figure 4
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  		Figure 4 Healthy dietary patterns contribute to a lower generation of a proinflammatory milieu, which in turn may decrease the incidence of metabolic syndrome, type 2 diabetes, and coronary heart disease (CHD). CRP = C-reactive protein; IL = interleukin; TNF = tumor necrosis factor.

 




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