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Course of Depressive Symptoms and Medication Adherence After Acute Coronary Syndromes

An Electronic Medication Monitoring Study

Nina Rieckmann, PhD^_*, William Gerin, PhD, Ian M. Kronish, MD, Matthew M. Burg, PhD, William F. Chaplin, PhD^||, Grace Kong, MA^||, François Lespérance, MD and Karina W. Davidson, PhD^,¶,_*

^_* Department of Psychiatry, Mount Sinai School of Medicine, New York, New York
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York
Division of General Internal Medicine, Mount Sinai School of Medicine, New York, New York
Department of Psychiatry, Centre Hospitalier de l’Université de Montréal, Montréal, Quebec, Canada
^|| Department of Psychology, St. Johns University, Queens, New York
^¶ Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York.

View larger version (20K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Flowchart of participants. MEMS = medication event monitoring system.

View larger version (11K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Proportion of nonadherent (aspirin taken <80% of days) patients in 3 groups: non-depressed (Beck Depression Inventory [BDI] score 0 to 4), mildly depressed (BDI 10 to 16), and moderately to severely depressed (BDI >16).

View larger version (23K): [in this window] [in a new window] [Download PPT slide]   Figure 3 Cross-lagged panel model testing the relationship between depression and adherence over time. **p < 0.01. ACS = acute coronary syndromes.