Metyrapone Improves Endothelial Dysfunction in Patients With Treated Depression
Andrew J.M. Broadley, MRCP*,
Ania Korszun, MRCPsych ,
Eltigani Abdelaal, MRCP*,
Valentina Moskvina, PhD ,
John Deanfield, FRCP ,
Christopher J.H. Jones, FRCP and
Michael P. Frenneaux, FRCP, FACC*,*
* Department of Cardiovascular Medicine, University of Birmingham, Birmingham, England
Department of Psychological Medicine, St. Bartholomews and Royal London Hospital School of Medicine, London, England
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, Wales
Department of Cardiology, Great Ormond Street Hospital for Children, London, England.

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Figure 1 Brachial artery diameter change over time profiles: patients and control subjects (morning flow-mediated dilation).
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Figure 2 Change in flow-mediated dilation (FMD) after placebo/metyrapone.
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