Validation and Re-Evaluation of a Discriminant Model Predicting Anatomic Suitability for Biventricular Repair in Neonates With Aortic Stenosis
Steven D. Colan, MDa,b,*,
Doff B. McElhinney, MDa,b,
Elizabeth C. Crawford, RDCSa,b,
John F. Keane, MDa,b and
James E. Lock, MDa,b
a Department of Cardiology, Childrens Hospital, Harvard Medical School, Boston, Massachusetts.
b Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

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Figure 1 Scatter plot showing discriminant scores (for the overall cohort of 126 patients) calculated with the originally published (1) discriminant equation (solid symbols) and our updated discriminant equation (open symbols). Reference lines show the optimal discriminant cutoffs of 0.35 (original model, solid line) and 0.65 (updated model, dashed line).
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Figure 2 Scatter plots showing pre-intervention z-scores for (A) aortic annulus diameter, (B) aortic root diameter, (C) left ventricular (LV) end-diastolic dimension (EDD), and (D) the LV long-axis to heart long-axis ratio (LAR). Survivors are depicted as solid circles and events are depicted as open symbols, with patients who died shown as open triangles and patients who survived after conversion to a functional SV circulation shown as open circles.
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