Tpeak-Tend and Tpeak-Tend Dispersion as Risk Factors for Ventricular Tachycardia/Ventricular Fibrillation in Patients With the Brugada Syndrome
Jesus Castro Hevia, MD*,
Charles Antzelevitch, PhD, FACC ,*,
Francisco Tornés Bárzaga, MD*,
Margarita Dorantes Sánchez, MD*,
Francisco Dorticós Balea, PhD*,
Roberto Zayas Molina, MD*,
Miguel A. Quiñones Pérez, MD* and
Yanela Fayad Rodríguez, MD*
* Arrhythmia Unit, Cardiovascular Surgery and Cardiology Institute, Havana, Cuba
Masonic Medical Research Laboratory, Utica, New York.
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Figure 1 Precordial leads of the electrocardiogram (ECG) of a patient with the Brugada syndrome with recurrences (A), a Brugada-type ECG (B), and a control case (C). Numbers depict measured values for QT, QTpeak (QTp) and Tpeak-Tend interval (Tp-e). All values are in ms. T waves <1.5 mm were not measured.
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Figure 2 Kaplan-Meier analysis of arrhythmic events during follow-up depending on Tpeak-Tend interval (Tp-e)  100 ms or Tp-e <100 ms.
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Figure 3 Tpeak-Tend interval (Tp-e) receiver-operating characteristic (ROC) curve. The cut point that better optimizes the values of sensibility and specificity are for values 100 ms.
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Figure 4 Kaplan-Meier analysis of arrhythmic events during follow-up depending on Tpeak-Tend interval (Tp-e) dispersion >20 ms or Tp-e dispersion  20 ms.
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Figure 5 Tpeak-Tend interval (Tp-e) dispersion receiver-operating characteristic (ROC) curve. The cut point that better optimizes the values of sensibility and specificity are for values >20 ms.
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