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Reproducibility of Chronic and Acute Infarct Size Measurement by Delayed Enhancement-Magnetic Resonance Imaging

Holger Thiele, MD^_*,_*, Mathias J.E. Kappl, MD^_*, Stefan Conradi, MD, Josef Niebauer, MD, PhD^_*, Rainer Hambrecht, MD^_* and Gerhard Schuler, MD^_*

^_* Department of Cardiology, University of Leipzig-Heart Center, Leipzig, Germany
Department of Radiology, University of Leipzig-Heart Center, Leipzig, Germany

View larger version (170K): [in a new window]   Figure 1 Short axis slice showing the endocardial (green), epicardial (yellow), papillary (blue), and infarcted contours (white) in a patient with inferior myocardial infarction.

View larger version (14K): [in a new window]   Figure 2 Bland-Altman reproducibility analysis for the overall patient population. Central horizontal dotted line = mean absolute difference or bias; upper and lower lines = 95% confidence intervals (limits of agreement); black diamonds = acute myocardial infarction (MI); white diamonds = chronic MI. IS = infarct size; %LV = percentage of LV volume.

View larger version (19K): [in a new window]   Figure 3 Bland-Altman analysis for intraobserver (A) and interobserver (B) variability. Central horizontal dotted line = mean absolute difference or bias; upper and lower lines = 95% confidence intervals (limits of agreement); diamonds = myocardial infarction (MI). Abbreviations as in Figure 2.