This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (31) Citing Articles via Google Scholar Google Scholar Articles by Butler, J. Search for Related Content PubMed PubMed Citation Articles by Butler, J.

Metabolic Syndrome and the Risk of Cardiovascular Disease in Older Adults

Javed Butler, MD, MPH, FACC^_*,_*, Nicolas Rodondi, MD, MAS^||, Yuwei Zhu, PhD, Kathleen Figaro, MD, MS, Sergio Fazio, MD, PhD^_*, Douglas E. Vaughan, MD, FACC^_*, Suzanne Satterfield, MD, Anne B. Newman, MD, MPH^#, Bret Goodpaster, PhD^#, Douglas C. Bauer, MD^||, Paul Holvoet, PhD^_**, Tamara B. Harris, MD, MS, Nathalie de Rekeneire, MD, Susan Rubin, MPH^¶, Jingzhong Ding, PhD, Stephen B. Kritchevsky, PhD for the Health ABC Study

^_* Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee
Department of Biostatistics, Vanderbilt University, Nashville, Tennessee
Division of General Internal Medicine, Vanderbilt University, Nashville, Tennessee
Department of Preventive Medicine, University of Tennessee, Memphis, Tennessee
^|| Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California
^¶ Prevention Sciences Group, University of California San Francisco, San Francisco, California
^# Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
^_** Center for Experimental Surgery and Anesthesiology, Catholic University, Leuven, Belgium
Laboratory of Epidemiology, Demography and Biometry, National Institute of Aging, National Institutes of Health, Bethesda, Maryland
Sticht Center on Aging, Wake Forest University School of Medicine, Winston-Salem, North Carolina

View larger version (25K): [in a new window]   Figure 1 Overall effect of metabolic syndrome (MetSyn) on cardiovascular outcomes and mortality. Point estimates of hazard ratios (HR) and 95% confidence intervals. Both unadjusted and covariate adjusted p values are shown. The covariates adjusted for included age, race (white and black), gender (male and female), smoking (never, past, and current), marital status (married, widow, and other), site (Memphis and Pittsburgh), and the presence of diabetes at baseline.

View larger version (33K): [in a new window]   Figure 2 Adjusted survival curves for myocardial infarction (MI), heart failure (CHF), coronary event, and overall hospital stay risk. The figures represent survival plots adjusted for age, gender, race, smoking status, marital status, site, and diabetes. Cum = cumulative; MetSyn = metabolic syndrome.