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Left Ventricular Systolic Dysfunction in Rheumatoid Disease

An Unrecognized Burden?

Gurbir S. Bhatia, MRCP^_*, Michael D. Sosin, MRCP^_*, Jeetesh V. Patel, PhD^_*, Karl A. Grindulis, FRCP, Fazal H. Khattak, FRCP, Elizabeth A. Hughes, BSc, FRCP, Gregory Y.H. Lip, MD, FRCP, FACC, FESC^_* and Russell C. Davis, MRCP, MD^_*,_*

^_* Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, England
Department of Rheumatology, Sandwell and West Birmingham Hospitals NHS Trust, Lyndon, West Bromwich, England
Department of Chemical Pathology, Sandwell and West Birmingham Hospitals NHS Trust, Lyndon, West Bromwich, England

View larger version (15K): [in a new window]   Figure 1 Box plots showing median plasma brain natriuretic peptide (BNP) levels (horizontal bars) for normal left ventricular (LV) function versus left ventricular systolic dysfunction (LVSD). Median BNP = 8.5 pmol/l (interquartile range, 8.8) in those with normal LV function versus 16.6 pmol/l (interquartile range, 26.1) in those with LVSD. LVEF = left ventricular ejection fraction.