Accuracy of 64-Slice Computed Tomography to Classify and Quantify Plaque Volumes in the Proximal Coronary System
A Comparative Study Using Intravascular Ultrasound
Alexander W. Leber, MD*, ,1,*,
Alexander Becker, MD*,
Andreas Knez, MD*,
Franz von Ziegler, MD*,
Marc Sirol, MD,
Konstantin Nikolaou, MD ,
Bernd Ohnesorge, PhD ,
Zahi A. Fayad, PhD,
Christoph R. Becker, MD,
Maximilian Reiser, MD,
Gerhard Steinbeck, MD* and
Peter Boekstegers, MD*
* Department of Cardiology, Klinikum Grosshadern, University of Munich, Munich, Germany
Institute for Diagnostic Radiology, Klinikum Grosshadern, University of Munich, Munich, Germany
Siemens Medical Solutions CT-Division, Forchheim, Germany
Mount Sinai Medical Center New York, Imaging Science Laboratory, New York, New York.
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Figure 1 Bland-Altman plot (A) and correlation graph (B) for plaque volumes per vessel determined by intravascular ultrasound (IVUS) versus 64-slice computed tomography (SCT). Vessel plaque volume is underestimated systematically by 64-slice computed tomography (p < 0.05), and correlation is moderate (Spearman correlation coefficient r2 = 0.69).
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Figure 2 Lipid core within a mixed plaque detected by intravascular ultrasound (IVUS) and 64-slice computed tomography (CT). ca = calcium; lc = lipid core.
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Figure 3 Noncalcified section with an embedded lipid core indicated by echolucency on intravascular ultrasound (IVUS) and hypodensity on 64-slice computed tomography (CT).
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