Treadmill Exercise Produces Larger Perfusion Defects Than Dipyridamole Stress N-13 Ammonia Positron Emission Tomography
Benjamin J.W. Chow, MD, FRCPC, FACC*, ,*,
Rob S. Beanlands, MD, FRCPC, FACC*, ,a,
Andrea Lee*,
Jean N. DaSilva, PhD*,
Robert A. deKemp, PhD*,
Abdulkareem Alkahtani, MD* and
Terrence D. Ruddy, MD, FRCPC, FACC*,
* Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Division of Nuclear Medicine, Ottawa Hospital, Ottawa, Ontario, Canada.

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Figure 1 Rest and stress N-13 ammonia positron emission tomography protocol.
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Figure 2 (A) Correlation of exercise and dipyridamole summed stress score (SSS). (B) Correlation of exercise and dipyridamole summed rest score (SRS). (C) Correlation of exercise and dipyridamole summed difference score (SDS).
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Figure 3 (A) Bland Altman SSS (treadmill exercise [TEX] vs. dipyridamole). (B) Bland Altman SRS (TEX vs. dipyridamole). (C) Bland Altman SDS (TEX vs. dipyridamole). SD = standard deviation; other abbreviations as in Figure 2.
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Figure 4 Larger stress defect with treadmill exercise than with dipyridamole stress. A mild (magenta) perfusion defect is present in the inferolateral wall and apex with dipyridamole stress. The size and severity (blue) of the defect is greater after exercise stress.
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