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Elevated Placental Growth Factor Levels Are Associated With Adverse Outcomes at Four-Year Follow-Up in Patients With Acute Coronary Syndromes

Timo Lenderink, MD^_*,,_*, Christopher Heeschen, MD, Stephan Fichtlscherer, MD, Stefanie Dimmeler, MD, Christian W. Hamm, MD^||, Andreas M. Zeiher, MD, Maarten L. Simoons, MD^_*, Eric Boersma, PhD^_* for the CAPTURE Investigators

^_* Department of Cardiology, Atrium Medical Centre, Heerlen, the Netherlands
Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands
Department of Surgery, Ludwig-Maximilians-University, Munich, Germany
Department of Cardiology, J. W. Goethe University, Frankfurt, Germany
^|| Department of Cardiology, Kerckhoff Heart Center, Bad Neuheim, Germany

View larger version (16K): [in a new window]   Figure 1 Bar graphs of the calculated annual incidence of death or non-myocardial infarction according to placental growth factor (PlGF) status grouped in quintiles.

View larger version (12K): [in a new window]   Figure 2 Kaplan-Meier curves of death during four-year follow-up according to placental growth factor status. In the right panel, 49 patients who died or experienced myocardial infarction (MI) before the 30-day follow-up were excluded. Dotted line = placental growth factor >27 ng/l.

View larger version (12K): [in a new window]   Figure 3 Kaplan-Meier curves of death or myocardial infarction (MI) during four-year follow-up according to placental growth factor status. In the right panel, 49 patients who died or experienced MI before the 30-day follow-up were excluded. Dotted line = placental growth factor >27 ng/l.