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Door-to-Balloon Time With Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction Impacts Late Cardiac Mortality in High-Risk Patients and Patients Presenting Early After the Onset of Symptoms

Bruce R. Brodie, MD, FACC^_*,_*, Charles Hansen, MA, Thomas D. Stuckey, MD, FACC^_*, Scott Richter, PhD, Debra S. VerSteeg, RN^_*, Navin Gupta, MD, FACC^_*, William E. Downey, MD, FACC^_* and Mark Pulsipher, MD, FACC^_*

^_* LeBauer Cardiovascular Research Foundation and the Moses Cone Heart and Vascular Center, Greensboro, North Carolina
Internal Medicine Residency Program, Moses H. Cone Memorial Hospital, Greensboro, North Carolina
Department of Mathematics, University of North Carolina at Greensboro, Greensboro, North Carolina

View larger version (21K): [in a new window]   Figure 1 Kaplan-Meier estimates of late cardiac survival in patients treated with primary percutaneous coronary intervention for ST-segment elevation myocardial infarction according to door-to-balloon times.

View larger version (14K): [in a new window]   Figure 2 Kaplan-Meier estimates of late cardiac survival in patients treated with primary percutaneous coronary intervention for ST-segment elevation myocardial infarction according to door-to-balloon times. (A) High-risk patients (Killip class 3 to 4, age >70 years, or anterior infarction). (B) Low-risk patients.

View larger version (12K): [in a new window]   Figure 3 Kaplan-Meier estimates of late cardiac survival after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction according to door-to-balloon times. (A) Patients presenting early after the onset of symptoms (3 h). (B) Patients presenting late after the onset of symptoms (>3 h).