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Association of Paraoxonase-1 Activity and Concentration With Angiographic Severity and Extent of Coronary Artery Disease

Marit Granér, MD^_*,_*, Richard W. James, MD, PhD, Juhani Kahri, MD, PhD^_*, Markku S. Nieminen, MD, PhD^_*, Mikko Syvänne, MD, PhD^_* and Marja-Riitta Taskinen, MD, PhD^_*

^_* Department of Internal Medicine, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland
Clinical Diabetes Unit, Division of Endocrinology and Diabetology, University Hospital, Geneva, Switzerland.

View larger version (20K): [in a new window]   Figure 1 Box plot shows median (horizontal lines), 25th to 75th percentiles (boxes), and 95th percentiles (whiskers) of paraoxonase-1 (PON1) activity (A) and PON1 concentration (B) by visual angiographic coronary artery disease (CAD) status.

View larger version (17K): [in a new window]   Figure 2 Relationship between paraoxonase-1 (PON1) activity tertile by global percent diameter stenosis (PDS) index (A), global extent index (B), and global atheroma burden index (C), respectively. For definition of the indexes, see the Methods section.