Rimonabant: A Cannabinoid Receptor Type 1 Blocker for Management of Multiple Cardiometabolic Risk Factors
Eli V. Gelfand, MD* and
Christopher P. Cannon, MD
,a,*
* Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts

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Figure 1 Change in body weight among subjects in the Rimonabant in Obesity (RIO)-Lipids study. Reprinted, with permission, from Despres et al. (62).
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Figure 2 Percentage of subjects achieving 10% weight loss at one year with rimonabant (solid bars) 20 mg/day versus placebo (open bars) in the first two Rimonabant in Obesity (RIO) trials among those completing the study.
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Copyright © 2006 by the American College of Cardiology Foundation.