Myocardial Contrast Echocardiography for the Detection of Coronary Artery Stenosis
A Prospective Multicenter Study in Comparison With Single-Photon Emission Computed Tomography
Paramjit Jeetley, MBChB, MRCP*,
Michael Hickman, MB, BS, MRCP*,
Otto Kamp, MD ,
Roberto M. Lang, MD ,
James D. Thomas, MD ,
Mani A. Vannan, MBBS||,
Jean Louis Vanoverschelde, MD¶,
Poll A. van der Wouw, MD# and
Roxy Senior, MD, DM, FRCP*,*
* Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, United Kingdom
VU University Medical Center, Amsterdam, the Netherlands
# Onzw Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands
University of Chicago, Chicago, Illinois
Cleveland Clinic Foundation, Cleveland, Ohio
|| University of California at Irvine, Irvine, California
¶ University Hospital Saint Luc, Brussels, Belgium.
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Figure 1 Comparison of myocardial contrast echocardiography (MCE) (solid bars) and single-photon emission computed tomography (SPECT) (open bars) in the detection of coronary artery disease.
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Figure 2 Comparison of MCE (solid bars) and SPECT (open bars) in the detection of coronary artery disease in the anterior circulation. Abbreviations as in Figure 1.
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Figure 3 Comparison of MCE (solid bars) and SPECT (open bars) in the detection of coronary artery disease in the posterior circulation. Abbreviations as in Figure 1.
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Figure 4 Apical three-chamber view demonstrating reversible perfusion defects (arrows) in the posterior wall, apex, and septum in a patient with multivessel disease (bottom). The top panel shows the corresponding resting study demonstrating normal perfusion.
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Figure 5 Agreement between SPECT and MCE in the detection of coronary artery disease (CAD). Abbreviations as in Figure 1.
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