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Overestimation of Platelet Aspirin Resistance Detection by Thrombelastograph Platelet Mapping and Validation by Conventional Aggregometry Using Arachidonic Acid Stimulation

Sinai Center for Thrombosis Research, Baltimore, Maryland

View larger version (12K): [in a new window]   Figure 1 Scatter plot showing 1 mmol/l arachidonic acid-induced platelet aggregation by light-transmittance aggregometry in individual healthy subjects (n = 6) (before and after aspirin therapy), compliant (n = 196) and non-compliant patients (n = 7) undergoing percutaneous interventions (PCIs) (before and after PCI), and patients with a history of stent thrombosis (SAT).

View larger version (13K): [in a new window]   Figure 2 Scatter plot showing 1 mmol/l arachidonic acid-induced platelet aggregation by thrombelastography in individual healthy subjects (n = 6) (before and after aspirin therapy), compliant (n = 196) and non-compliant patients (n = 7) undergoing percutaneous interventions (PCIs) (before and after PCI), and patients with a history of stent thrombosis (SAT).