Abnormal Vasomotor Function of the Epicardial Coronary Arteries in Children Five to Eight Years After Arterial Switch Operation
An Angiographic and Intracoronary Doppler Flow Wire Study
Maria Giulia Gagliardi, MD, PhD*,*,
Rachele Adorisio, MD*,
Filippo Crea, MD ,
Paolo Versacci, MD*,
Roberto Di Donato, MD* and
Stephen P. Sanders, MD, FACC*
* Ospedale Bambino Gesù, Rome, Italy
Policlinico Universitario A. Gemelli Università La Cattolica, Rome, Italy

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Figure 1 Bar graphs showing the mean diameters of left anterior descending (LAD) coronary artery (top) and right coronary artery (RCA) (bottom) before and after nitroglycerin in arterial switch operation (ASO) and control patients. Gray bars = before nitroglycerin; black bars = after nitroglycerin.
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Figure 2 Plot of vessel diameter before and after nitroglycerin administration. The dots indicate the individual value of vessel diameter for both the ASO group (left) and the control group (right). Circles = LCA; triangles = RCA.
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Figure 3 Flow profiles before (left) and after (right) intracoronary injection of acetylcholine in a patient after the arterial switch operation (upper) and in a control patient (lower).
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Figure 4 Flow profiles before (left) and after (right) intracoronary injection of adenosine in a patient after the arterial switch operation (upper) and in a control patient (lower).
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