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J Am Coll Cardiol, 2005; 46:1249-1257, doi:10.1016/j.jacc.2005.06.056 (Published online 10 September 2005).
© 2005 by the American College of Cardiology Foundation
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Circulating Secretory Phospholipase A2 Activity Predicts Recurrent Events in Patients With Severe Acute Coronary Syndromes

Ziad Mallat, MD, PhD*,*, Ph. Gabriel Steg, MD, PhD{dagger}, Joëlle Benessiano, MD, PhD{ddagger}, Marie-Laure Tanguy, PhD§, Keith A. Fox, FESC||, Jean-Philippe Collet, MD, PhD, Omar H. Dabbous, MD, MPH#, Patrick Henry, MD**, Kathryn F. Carruthers, MPhil||, Anne Dauphin, MSc{ddagger}, Carla Sibella Arguelles, MSc{ddagger}, Joëlle Masliah, PhD{dagger}{dagger}, Bénédicte Hugel, PhD{ddagger}{ddagger}, Gilles Montalescot, MD, PhD, Jean-Marie Freyssinet, PhD{ddagger}{ddagger}, Bernard Asselain, PhD§ and Alain Tedgui, PhD*

* Institut National de la Santé et la Recherche Médicale, (INSERM U541), Institut Fédératif de Recherche (IRF) "Circulation," Paris, France
{dagger} Service de Cardiologie, Hôpital Bichat, Paris, France
{ddagger} Centre d’Investigation Clinique, CIC 07, Hôpital Bichat, Paris, France
§ Département de Biostatistiques, Institut Curie, Paris, France
Service de Cardiologie, Hôpital Pitié-Salpêtrière, Paris, France
** Service de Cardiologie, Hôpital Lariboisière, Paris, France
{dagger}{dagger} Service de Biochimie, Hôpital St. Antoine, Paris, France
{ddagger}{ddagger} Institut d’Hématologie et d’Immunologie, Faculté de Médecine, Université Louis Pasteur, Strasbourg, and INSERM U143, Le Kremlin-Bicêtre, France
|| Cardiovascular Research Unit, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom
# University of Massachusetts Medical School, Worcester, Massachusetts



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Figure 1 Kaplan-Meier curves showing the cumulative incidence of death or myocardial infarction (MI) according to the tertile of secretory type II phospholipase A2 (PLA2) activity.

 




 
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