Reversal of Inappropriate Peripheral Vascular Responses in Hypertrophic Cardiomyopathy
Rajesh Thaman, MD, MRCP*, ,*,
Perry M. Elliott, MD, MRCP, FACC*,,
Jaymin S. Shah, MD, MRCP*,,
Bryan Mist, PhD*,,
Lynne Williams, MRCP ,
Ross T. Murphy, MD, MRCP*,,
William J. McKenna, MD, FRCP, FACC*, and
Michael P. Frenneaux, MD, FRCP, FACC
* Department of Cardiological Sciences, St. George’s Hospital Medical School, London, United Kingdom
The Heart Hospital, University College London, London, United Kingdom
Department of Cardiovascular Medicine, University of Birmingham, Birmingham, United Kingdom
View larger version (15K):
[in a new window]
|
Figure 1 Change in forearm vascular resistance (FVR) before and during lower body negative pressure (LBNP) at baseline and after medication. Box and whisker plot for the change in FVR during LBNP in each treatment arm. The boxes represent the median and interquartile range for each treatment arm (median ± interquartile range = –6 ± 15, –5 ± 9, 3 ± 53, 4 ± 15, 6 ± 46 for baseline, placebo, propranolol, clonidine, and paroxetine, respectively). Whiskers represent the maximum and minimum values for each treatment arm.
|
|
View larger version (12K):
[in a new window]
|
Figure 2 Change in forearm vascular resistance (FVR) before and during lower body negative pressure (LBNP) at baseline and after medication. Box and whisker plot for the change in FVR during LBNP in each treatment arm. The boxes represent the median and interquartile range for each treatment arm (median ± interquartile range = 7.0 ± 15.0, 5.5 ± 10.0, 6.0 ± 25.0, 5.0 ± 25.0, 6.0 ± 50.0 for baseline, placebo, propranolol, clonidine, and paroxetine, respectively). Whiskers represent the maximum and minimum values for each treatment arm.
|
|
|
