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Long-Term Clinical Outcome After Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Multivessel Disease

Alexandre Berger, MD^_*, Kees-Joost Botman, MD^_*, Philip A. MacCarthy, MD, PhD, MRCP^_*, William Wijns, MD, PhD^_*, Jozef Bartunek, MD, PhD^_*, Guy R. Heyndrickx, MD, PhD^_*, Nico H.J. Pijls, MD, PhD and Bernard De Bruyne, MD, PhD^_*,_*

^_* Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium
Catharina Hospital, and the Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

View larger version (19K): [in a new window]   Figure 1 Individual values of fractional flow reserve (FFR) and individual values of the percent diameter stenosis (%DS) in treated and deferred arteries. The black dots indicate the stenoses responsible for a major adverse cardiac events at follow-up. Mean values are shown in both groups (bar). The dotted line indicates the cut-off value of FFR (0.75).

View larger version (18K): [in a new window]   Figure 2 Cumulative major adverse cardiac events (combined end points of death, myocardial infarction, and target vessel revascularization) rate curves (Kaplan-Meier) for treated, deferred vessels, and for the entire patient population.