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Mean Platelet Volume on Admission Predicts Impaired Reperfusion and Long-Term Mortality in Acute Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

Zenon Huczek, MD^_*,_*, Janusz Kochman, MD^_*, Krzysztof J. Filipiak, MD, PhD^_*, Grzegorz J. Horszczaruk, MD^_*, Marcin Grabowski, MD^_*,, Radoslaw Piatkowski, MD^_*, Joanna Wilczynska, MD, PhD^_*, Andrzej Zielinski, MD^_*, Bernhard Meier, MD, FACC, FESC and Grzegorz Opolski, MD, PhD, FESC^_*

^_* 1st Department of Cardiology, The Medical University of Warsaw, Warsaw, Poland
Department of Medical Informatics, The Medical University of Warsaw, Warsaw, Poland
Department of Cardiology, Swiss Cardiovascular Center, Bern, Switzerland.

View larger version (15K): [in a new window]   Figure 1 The receiver-operating characteristic (ROC) curve for mean platelet volume (MPV) for predicting angiographic no-reflow. The area under the ROC curve = 0.76 (95% confidence interval 0.72 to 0.80).

View larger version (15K): [in a new window]   Figure 2 Association of mean platelet volume (MPV) in conjunction with troponin I, with the frequency of no-reflow phenomenon.

View larger version (18K): [in a new window]   Figure 3 Correlation between admission mean platelet volume (MPV) and corrected TIMI frame count (CTFC) assessed on final angiogram.

View larger version (13K): [in a new window]   Figure 4 Kaplan-Meier curves for all-cause mortality according to mean platelet volume (MPV). The six-month all-cause mortality was 12.1% in high MPV versus 5.1% in low MPV.