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Left Ventricular Dyssynchrony Predicts Right Ventricular Remodeling After Cardiac Resynchronization Therapy

Gabe B. Bleeker, MD^_*,, Martin J. Schalij, MD, PhD^_*, Petros Nihoyannopoulos, MD, Paul Steendijk, PhD^_*, Sander G. Molhoek, MD^_*, Lieselot van Erven, MD, PhD^_*, Marianne Bootsma, MD, PhD^_*, Eduard R. Holman, MD, PhD^_*, Ernst E. van der Wall, MD, PhD^_* and Jeroen J. Bax, MD, PhD^_*,_*

^_* Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands
Interuniversity Cardiology Institute of the Netherlands (ICIN), Utrecht, the Netherlands
Imperial College London, NHLI and Cardiothoracic Directorate, Hammersmith Hospital, London, United Kingdom.

View larger version (78K): [in a new window]   Figure 1 Apical four-chamber two-dimensional echocardiogram. Schematic display of parameters reflecting right ventricular (RV) end-diastolic chamber size. LAX = long-axis; SAX = short-axis; TV ANN = tricuspid valve annulus.

View larger version (17K): [in a new window]   Figure 2 (A) Tricuspid valve annulus (TV ANN) at baseline and after six months of cardiac resynchronization therapy (CRT). Patients are divided into quartiles according to baseline TV ANN. (B) Right ventricular (RV) short-axis (SAX) at baseline and after six months of CRT. Patients are divided into quartiles according to baseline RV SAX. (C) Right ventricular long-axis (LAX) at baseline and after six months of CRT. Patients are divided into quartiles according to baseline RV LAX. Open bars = baseline; solid bars = six-month follow-up. *p < 0.05.