Coronary Calcification, Coronary Disease Risk Factors, C-Reactive Protein, and Atherosclerotic Cardiovascular Disease Events
The St. Francis Heart Study
Yadon Arad, MD, FACC,
Kenneth J. Goodman, MD,
Marguerite Roth, RN,
David Newstein, DrPh and
Alan D. Guerci, MD, FACC*
Research Department, St. Francis Hospital, Roslyn, New York.
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Figure 1 Flow diagram of the St. Francis Heart Study. Follow-up was available at 4.3 years on 4,613 of the 4,903 (94%) and 1,293 of the 1,357 (95%) eligible subjects in whom risk factors were measured. CRP = C-reactive protein; CT = computed tomographic; RCT = randomized clinical trial.
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Figure 2 Sensitivity (circles) and specificity (squares) for the prediction of all coronary disease events as a function of the square root of the coronary calcium score (n = 4,613).
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Figure 3 Coronary event rates as a function of calcium score within the Framingham risk groups (low: <10% per 10 years; intermediate: 10% to 20% per 10 years; and high: >20% per year). There were no coronary events in the first and second tertile of calcium scores in the Framingham low-risk group (n = 1,293).
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