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Elevation of Endothelial Microparticles, Platelets, and Leukocyte Activation in Patients With Venous Thromboembolism

Julio A. Chirinos, MD^_*,,_*, Gustavo A. Heresi, MD^_*, Hermes Velasquez, MD^_*, Wenche Jy, PhD^_*,, Joaquin J. Jimenez, MD^_*,, Eugene Ahn, MD^_*,, Lawrence L. Horstman, BS^_*,, Andres O. Soriano, MD^_*, Juan P. Zambrano, MD^_* and Yeon S. Ahn, MD^_*,

^_* Department of Medicine, University of Miami, Miami, Florida
Wallace H. Coulter Platelet Laboratory, University of Miami, Miami, Florida

View larger version (15K): [in a new window]   Figure 1 (A to C) Levels of EMP31 (A), EMP62E (B), and EMP-monocyte conjugates in subjects with venous thromboembolism (VTE) compared with normal controls. EMP = endothelial microparticles; FL = fluorescence.

View larger version (15K): [in a new window]   Figure 2 (A to C) Surface expression of P-selectin (CD62P) in platelets (A), CD11b in leukocytes (B), and levels of platelet-leukocyte conjugates in subjects with venous thromboembolism (VTE) compared with healthy controls. FL = fluorescence.

View larger version (17K): [in a new window]   Figure 3 Correlation on CD11b expression in leukocytes and levels of platelet-leukocyte conjugates in subjects with venous thromboembolism.