Increased Ambulatory Pulse Pressure Is a Strong Risk Factor for Coronary Endothelial Vasomotor Dysfunction
Yoshihide Ichigi, MD,
Hajime Takano, MD, PhD,
Ken Umetani, MD, PhD,
Kenichi Kawabata, MD, PhD,
Jyun-ei Obata, MD, PhD,
Yoshinobu Kitta, MD,
Yasushi Kodama, MD,
Akira Mende, MD,
Takamitsu Nakamura, MD,
Daisuke Fujioka, MD,
Yukio Saito, MD and
Kiyotaka Kugiyama, MD, PhD*
Department of Internal Medicine II, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.

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Figure 1 Correlations of 24-h ambulatory pulse pressure (PP) with percent (%) changes of epicardial coronary dilator responses to acetylcholine (50 µg/min) in all the study patients, hypertensive patients, and normotensive patients.
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Figure 2 Correlations of 24-h ambulatory pulse pressure (PP) with percent (%) changes of coronary blood flow responses to acetylcholine (5 µg/min) in all the study patients, hypertensive patients, and normotensive patients.
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