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J Am Coll Cardiol, 2005; 45:712-719, doi:10.1016/j.jacc.2004.10.068
© 2005 by the American College of Cardiology Foundation
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Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol

The Losartan Intervention For End point reduction in hypertension (LIFE) study

Kristian Wachtell, MD, PhD*,{dagger},*, Mika Lehto, MD{ddagger}, Eva Gerdts, MD, PhD§, Michael H. Olsen, MD, PhD*, Björn Hornestam, MD||, Björn Dahlöf, MD, PhD, FACC||, Hans Ibsen, MD*, Stevo Julius, MD, FACC, Sverre E. Kjeldsen, MD, PhD, FACC,#, Lars H. Lindholm, MD, FACC**, Markku S. Nieminen, MD, FACC{ddagger} and Richard B. Devereux, MD, FACC{dagger}

* Department of Medicine, Glostrup University Hospital, Glostrup, Denmark
{dagger} Division of Cardiology, Weill Medical College of Cornell University, New York, New York
{ddagger} Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland
§ Department of Cardiology, Haukeland University Hospital, Bergen, Norway
|| Department of Medicine, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden
Department of Medicine, University of Michigan, Ann Arbor, Michigan
# Department of Medicine, Ullevål University Hospital, Oslo, Norway
** Department of Preventive Medicine, Umeå University Hospital, Umeå, Sweden



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  		Figure 1 Trial profile.

 


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  		Figure 2 Kaplan-Meier curves illustrating new-onset electrocardiogram-verified atrial fibrillation during follow-up. CI = confidence interval; HR = hazard ratio.

 




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