Angioscopic follow-up study of coronary ruptured plaques in nonculprit lesions
Masamichi Takano, MD,
Shigenobu Inami, MD,
Fumiyuki Ishibashi, MD,
Kentaro Okamatsu, MD,
Koji Seimiya, MD,
Takayoshi Ohba, MD,
Shunta Sakai, MD and
Kyoichi Mizuno, MD, PhD, FACC*
Department of Internal Medicine, Chiba-Hokusoh Hospital, Nippon Medical School, Chiba, Japan
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Figure 1 Angioscopic images of nonculprit ruptured plaques. (A) Yellow plaque with a fissure (arrow) and red thrombus. (B) Yellow plaque with a flap (arrow). (C) Yellow plaque with an ulceration (arrow) and red thrombus. (D) Yellow plaque with a pinkish-white thrombus (arrow).
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Figure 2 Healing of nonculprit plaque in acute coronary syndrome (ACS). (A) Coronary angiogram of the left circumflex artery (LCx) in a patient with ACS. (B) A pinkish-white thrombus on the yellow plaque was observed in the mid-portion of the LCx at baseline (white arrowhead in A). (C) A 12-month follow-up coronary angiogram in the same patient. (D) The thrombus disappeared and a smooth white intima was found (white arrowhead in C). In the quantitative coronary angiogram measurements, %DS at the angioscopic image site (white arrowhead in A and C) increased from 34.5% at baseline to 43.1% at follow-up.
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Figure 3 Relationship between the angioscopic follow-up period and healing rate of the nonculprit ruptured plaques. The healing rate of ruptured plaques of  12 months and >12 months were 23% and 55%, respectively. The healing rate increased according to the angioscopic follow-up period.
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