Heart rate turbulence after atrial premature beats before spontaneous onset of atrial fibrillation
Saila Vikman, MD*,*,
Kai Lindgren, MD ,
Timo H. Mäkikallio, MD ,
Sinikka Yli-Mäyry, MD*,
K.E. Juhani Airaksinen, MD and
Heikki V. Huikuri, MD, FACC
* Heart Center, University Hospital of Tampere, Tampere, Finland
Division of Cardiology, Department of Medicine, University of Oulu, Oulu, Finland
Division of Cardiology, Department of Medicine, University of Turku, Turku, Finland

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Figure 1 Heart rate turbulence onset (TO) after spontaneous atrial premature beats. The value of TO is significantly less negative during the 1 h preceding atrial fibrillation (AF) than the hourly mean values of the non-AF hours of the recording both in patients with lone AF (left) and in patients with structural heart diseases (right).
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Figure 2 Heart rate turbulence onset (TO) after spontaneous atrial premature beats in 15-min periods during the 1 h preceding atrial fibrillation (AF) episode(s). In the subgroup of patients (n = 15; 17 recordings) with at least one atrial ectopic beat in each 15-min period during the hour preceding an AF episode, TO is significantly less negative during the 0- to 15-min period before AF than during the 45- to 60-min period preceding AF.
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