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Contribution of ischemic mitral regurgitation to congestive heart failure after myocardial infarction

Francesco Grigioni, MD^*, Delphine Detaint, MD^*, Jean-François Avierinos, MD^*, Christopher Scott, MS, Jamil Tajik, MD, FACC^* and Maurice Enriquez-Sarano, MD, FACC^*,*

^* Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota
Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

View larger version (14K): [in a new window]   Figure 1 Incidence of congestive heart failure (CHF) in asymptomatic patients after myocardial infarction (MI) according to the presence (continuous line) or absence (dotted line) of ischemic mitral regurgitation (IMR) at diagnosis. The event rates at five years are indicated ± the standard error.

View larger version (16K): [in a new window]   Figure 2 Incidence of congestive heart failure (CHF) in asymptomatic patients after myocardial infarction according to the degree of mitral regurgitation measured by effective regurgitant orifice (ERO) 20 mm2 (continuous line), 1 to 19 mm2 (dotted line), and absent mitral regurgitation (ERO = 0) (dashed line) at diagnosis. The event rates at five years are indicated ± the standard error.

View larger version (14K): [in a new window]   Figure 3 Survival free of congestive heart failure or cardiac death (event-free survival) in asymptomatic patients after myocardial infarction (MI) according to the presence (continuous line) or absence (dotted line) of ischemic mitral regurgitation (IMR) at diagnosis. The event-free survival rates at five years are indicated ± the standard error.

View larger version (14K): [in a new window]   Figure 4 Survival free of congestive heart failure or cardiac death (event-free survival) in asymptomatic patients after myocardial infarction according to the degree of mitral regurgitation measured by effective regurgitant orifice (ERO) 20 mm2 (continuous line), 1 to 19 mm2 (dashed line), and absent mitral regurgitation (ERO = 0) (dotted line) at diagnosis. The event-free survival rates at five years are indicated ± the standard error.