Inhibition of Awake Sympathetic Nerve Activity of Heart Failure Patients With Obstructive Sleep Apnea by Nocturnal Continuous Positive Airway Pressure
Kengo Usui, MD, PhD,
T. Douglas Bradley, MD, FRCPC,
Jonas Spaak, MD, PhD,
Clodagh M. Ryan, MB, BCh,
Toshihiko Kubo, MD, PhD,
Yasuyuki Kaneko, MD and
John S. Floras, MD, DPhil, FRCPC, FACC*
University Health Network and Mount Sinai Hospital Department of Medicine and Sleep Research Laboratories of the Toronto Rehabilitation Institute, University of Toronto, Toronto, Canada.
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Figure 1 Baseline and one-month muscle sympathetic nerve activity (MSNA) and electro tracings from a control subject and a subject randomized to continuous positive airway pressure (CPAP). ECG = electrocardiogram.
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Figure 2 Individual values and means ± SE for muscle sympathetic nerve activity (MSNA) burst frequency at baseline and after one month in control patients (left) and continuous positive airway pressure (CPAP)-treated subjects (right).
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