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Plant Sterols in Serum and in Atherosclerotic Plaques of Patients Undergoing Carotid Endarterectomy

Tatu A. Miettinen, MD, PhD^_*,_*, Mikael Railo, MD, PhD, Mauri Lepäntalo, MD, PhD and Helena Gylling, MD, PhD^,

^_* Department of Medicine, Division of Internal Medicine, University of Helsinki, Helsinki, Finland
Department of Medicine, Vascular Surgery, University of Helsinki, Helsinki, Finland
Department of Clinical Nutrition, University of Kuopio, Kuopio, Finland
Kuopio University Hospital, Kuopio, Finland

View larger version (44K): [in a new window]   Figure 1 Cholesterol and non-cholesterol sterol concentrations and esterification in carotid artery wall in triads by tissue cholesterol concentration. Absolute values (mg/100 g of tissue for cholesterol and µg/100 g of tissue for non-cholesterol sterols) of free sterols are given on top, and those of esterified ones at bottom of each column. Esterification percentages of tissue sterols, mean ± SE, are given by continuous horizontal lines, and those of respective serum values by dashed lines without given data.

View larger version (18K): [in a new window]   Figure 2 Correlation of serum ratios of campesterol (upper panel) and lathosterol (lower panel) to cholesterol with those of tissue campesterol (p < 0.001 for both).