Noninvasive Home Telemonitoring for Patients With Heart Failure at High Risk of Recurrent Admission and Death
The Trans-European Network-Home-Care Management System (TEN-HMS) study
John G.F. Cleland, MD*,*,
Amala A. Louis, MD*,
Alan S. Rigby, PhD*,
Uwe Janssens, MD ,
Aggie H.M.M. Balk, MD TEN-HMS Investigators
* University of Hull, Kingston Upon Hull, United Kingdom
Universitätsklinikum, Aachen, Germany
Thoraxcenter, Erasmus MC, Rotterdam, the Netherlands
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Figure 1 Diagrammatic representation of the telemonitoring system used in the trial. ECG = electrocardiogram.
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Figure 2 Consort diagram showing distribution, follow-up, and outcome of patients.
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Figure 3 Mortality in each of the randomized groups. A difference was found between usual care and either nurse telephone support or home telemonitoring (chi-squared test: p = 0.0397). The absolute difference in mortality at one year was 16% to 18%. Dashed line = usual care; dotted line = nurse support; solid line = telemonitoring.
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Figure 4 Overall mortality for patients with patients in the lowest (tercile 1: <1,742 pg/ml), mid- (tercile 2: 1,743 to 5,210 pg/ml), and highest (tercile 3: >5,211 pg/ml) tercile of N-terminal pro-brain natriuretic peptide; p = 0.0006 (chi-squared test) for the difference. Dotted line = tercile 1; dashed line = tercile 2; solid line = tercile 3.
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