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J Am Coll Cardiol, 2005; 45:1594-1599, doi:10.1016/j.jacc.2005.01.053
© 2005 by the American College of Cardiology Foundation
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Multiple Plaque Rupture and C-Reactive Protein in Acute Myocardial Infarction

Atsushi Tanaka, MD*,*, Kenei Shimada, MD{dagger}, Toshihiko Sano, MD*, Masashi Namba, MD*, Tsunemori Sakamoto, MD*, Yukio Nishida, MD*, Takahiko Kawarabayashi, MD*, Daiju Fukuda, MD{dagger} and Junichi Yoshikawa, MD, FACC{dagger}

* Baba Memorial Hospital, Sakai, Japan
{dagger} Department of Internal Medicine and Cardiology Graduate School of Medicine, Osaka City University, Osaka, Japan



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Figure 1 A representative case of multiple plaque rupture. Plaque rupture were observed in the proximal left descending coronary artery and mid portion of the right coronary artery.

 


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Figure 2 Relationship between the number of plaque ruptures and high sensitivity C-reactive protein (hs-CRP) levels. At one month from onset, the number of plaque ruptures showed a positive correlation with hs-CRP levels (r = 0.68, p < 0.01).

 


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Figure 3 Event-free survival curve. The Kaplan-Meier curve showed that the multiple-plaque rupture group was associated with poor clinical outcomes as compared with the other groups at two years (p = 0.01). Solid line = multiple-plaque rupture; dashed line = single rupture; dotted line = nonrupture.

 





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