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Multiple Plaque Rupture and C-Reactive Protein in Acute Myocardial Infarction

Atsushi Tanaka, MD^_*,_*, Kenei Shimada, MD, Toshihiko Sano, MD^_*, Masashi Namba, MD^_*, Tsunemori Sakamoto, MD^_*, Yukio Nishida, MD^_*, Takahiko Kawarabayashi, MD^_*, Daiju Fukuda, MD and Junichi Yoshikawa, MD, FACC

^_* Baba Memorial Hospital, Sakai, Japan
Department of Internal Medicine and Cardiology Graduate School of Medicine, Osaka City University, Osaka, Japan

View larger version (134K): [in a new window]   Figure 1 A representative case of multiple plaque rupture. Plaque rupture were observed in the proximal left descending coronary artery and mid portion of the right coronary artery.

View larger version (14K): [in a new window]   Figure 2 Relationship between the number of plaque ruptures and high sensitivity C-reactive protein (hs-CRP) levels. At one month from onset, the number of plaque ruptures showed a positive correlation with hs-CRP levels (r = 0.68, p < 0.01).

View larger version (14K): [in a new window]   Figure 3 Event-free survival curve. The Kaplan-Meier curve showed that the multiple-plaque rupture group was associated with poor clinical outcomes as compared with the other groups at two years (p = 0.01). Solid line = multiple-plaque rupture; dashed line = single rupture; dotted line = nonrupture.