Discordant atrial natriuretic peptide and brain natriuretic peptide levels in lone atrial fibrillation
Patrick T. Ellinor, MD, PhD,
Adrian F. Low, MB, BS,
Kristen K. Patton, MD,
Marisa A. Shea, RN and
Calum A. MacRae, MB, ChB, PhD*
Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts

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Figure 1 Box plots illustrating the median levels of nt-pro-brain natriuretic peptide (nt-proBNP) (A) and pro-atrial natriuretic peptide (proANP) (B) in subjects with lone atrial fibrillation (LAF) and in healthy control subjects. Boxes show interquartile ranges, and the bars represent the 10th and 90th percentiles.
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Figure 2 Box plot illustrating the median level of nt-pro-brain natriuretic peptide (nt-proBNP) (A) and pro-atrial natriuretic peptide (pro-ANP) (B) in controls subjects versus patients with paroxysmal or permanent lone atrial fibrillation (AF). Subjects with paroxysmal AF (PAF) were stratified according to the rhythm at the time of sampling. Boxes show interquartile ranges, and the bars represent the 10th and 90th percentiles. In B, there was no statistically significant difference between any of the groups. AFl = atrial flutter; NSR = normal sinus rhythm; SB = sinus bradycardia.
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