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An increase of C-reactive protein is associated with enhanced activation of endogenous fibrinolysis at baseline but an impaired endothelial fibrinolytic response after venous occlusion

Walter Stefan Speidl, MD^*, Andrea Zeiner, MD, Mariam Nikfardjam, MD^*, Alexander Geppert, MD, Nelli Jordanova, MD, Alexander Niessner, MD^*, Gerlinde Zorn, BSc^*, Gerald Maurer, MD, FACC^*, Wolfgang Schreiber, MD, Johann Wojta, PhD^* and Kurt Huber, MD, FACC^,*

^* Department of Internal Medicine II, Medical University of Vienna and the Ludwig Boltzmann Foundation for Cardiovascular Research, Vienna, Austria
Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria
3rd Department of Medicine (Cardiology and Emergency Medicine), Wilhelminenspital, Vienna, Austria

View larger version (14K): [in a new window]   Figure 1 Correlation of relative increase of tissue-type plasminogen activator (t-PA) activity with plasma levels of C-reactive protein (CRP) during a standardized venous occlusion (VO) test of the forearm.