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Direct stenting of native de novo coronary artery lesions with the sirolimus-eluting stent

A post hoc subanalysis of the pooled E- and C-SIRIUS trials

Michael Schlüter, PhD^*, Joachim Schofer, MD^*,*, Anthony H. Gershlick, MD, Erick Schampaert, MD, William Wijns, MD, Günter Breithardt, MD, FACC^|| for the E- and C-SIRIUS Investigators

^* Center for Cardiology and Vascular Intervention, Hamburg, Germany
Glenfield Hospital, Leicester, United Kingdom
Hôpital du Sacré-Coeur de Montréal, Montréal, Canada
Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium
^|| Department of Cardiology and Angiology, Hospital of the University of Münster, Münster, Germany

View larger version (16K): [in a new window]   Figure 1 Mean eight-month late loss at the proximal (Prox.) stent margin, within the stent, and at the distal (Dist.) stent margin. Open bars = predilated lesions; solid bars = directly stented lesions.

View larger version (12K): [in a new window]   Figure 2 Rates of major adverse cardiac events (MACE) and target lesion revascularization (TLR) at one year. Both clinical outcome variables are markedly, although non-significantly, reduced in patients who underwent DS (solid bars). Open bars = predilation.