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Diagnostic performance of coronary magnetic resonance angiography as compared against conventional x-ray angiography

A meta-analysis

Peter G. Danias, MD, PhD, FACC^*,,,*, Arkadios Roussakis, MD and John P.A. Ioannidis, MD^,||

^* *2nd Cardiology Clinic
Cardiac MRI Center, Hygeia Hospital, Athens, Greece; Department of Medicine
Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Clinical Trials and Evidence-Based Medicine Unit and Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine and the Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece
^|| Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, Boston, MassachusettsUSA

View larger version (21K): [in a new window]   Figure 1 Summary receiver-operating characteristic (SROC) curves for the diagnostic performance of coronary magnetic resonance angiography against the gold standard of X-ray coronary angiography using segment-level (A), vessel-level (B), and subject-level (C) data. Each ellipse corresponds to a comparison. Within each panel the diameters of the ellipses are inversely proportional to the variance of the sensitivity (vertical diameter) and the variance of specificity (horizontal diameter) of each comparison. Also shown is the independently weighted sensitivity and specificity according to random effects calculations (x) as well as the 95% confidence intervals (box). Weighted SROC curves are shown with bold lines; unweighted SROC curves are shown by thin lines.

View larger version (27K): [in a new window]   Figure 2 Summary receiver-operating characteristic curves for the diagnostic performance of coronary magnetic resonance angiography against the gold standard of X-ray angiography using segment-level data according to coronary vessel: left main (A), left anterior descending (B), left circumflex (C), and right (D) coronary arteries. Setup as in Figure 1.