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Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction

The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial

Michael G. McLaughlin, MD^*, Gregg W. Stone, MD, FACC, Eve Aymong, MD, MS, Graham Gardner, MD^*, Roxana Mehran, MD, FACC, Alexandra J. Lansky, MD, FACC, Cindy L. Grines, MD, FACC, James E. Tcheng, MD, FACC, David A. Cox, MD, FACC^||, Thomas Stuckey, MD, FACC^¶, Eulogio Garcia, MD^#, Giulio Guagliumi, MD^**, Mark Turco, MD, FACC, Mark E. Josephson, MD, FACC^* and Peter Zimetbaum, MD, FACC^*,*

^* Beth Israel Deaconess Medical Center, Boston, Massachusetts
Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, New York, New York, USA
William Beaumont Hospital, Royal Oak, Michigan, USA
Duke Clinical Research Institute, Durham, North Carolina, USA
^|| Mid Carolina Cardiology, Charlotte, North Carolina, USA
^¶ Moses Cone Memorial Hospital, Greensboro, North Carolina, USA
^# Hospital Gregorio Maranon, Madrid, Spain
^** Ospedali Riuniti di Bergamo, Bergamo, Italy
Doylestown Hospital, Doylestown, Pennsylvania, USA

View larger version (31K): [in a new window]   Figure 1 Reasons for exclusion from the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) ST-segment substudy. ECG = electrocardiogram.

View larger version (18K): [in a new window]   Figure 2 Distribution of ST-segment elevation and ST-segment elevation resolution (STR) measurements.

View larger version (23K): [in a new window]   Figure 3 Percentage of patients in each ST-segment elevation and ST-segment elevation resolution (STR) category with Thrombolysis In Myocardial Infarction (TIMI) flow grade 3.

View larger version (29K): [in a new window]   Figure 4 Multivariate ST-segment elevation resolution predictors of 30-day outcomes for mortality (top), reinfarction (middle), and the combined end point (bottom). CI = confidence interval; STR = ST-segment elevation resolution.

View larger version (29K): [in a new window]   Figure 5 Multivariate ST-segment elevation resolution predictors of one-year outcomes for mortality (top), reinfarction (middle), and the combined end point (bottom). Abbreviations as in Figure 4.