Prognostic role of B-type natriuretic peptide levels in patients with type 2 diabetes mellitus
Meenakshi A. Bhalla, MD*,
Audrey Chiang, MD*,
Victoria A. Epshteyn, MD*,
Radmila Kazanegra, MD*,
Vikas Bhalla, MD*,
Paul Clopton, MS*,
Padma Krishnaswamy, MD*,
L.K. Morrison, BS*,
Albert Chiu, BS*,
Nancy Gardetto, NPN*,
Sunder Mudaliar, MD ,
Steven V. Edelman, MD,
Robert R. Henry, MD and
Alan S. Maisel, MD ,*
* Division of Cardiology, San Diego, San Diego, California, USA
Division of Endocrinology, San Diego, San Diego, California, USA
Division of Department of Medicine Veteran’s Affairs Medical Center and University of California, San Diego, San Diego, California, USA
View larger version (32K):
[in a new window]
|
Figure 1 Shows the median B-natriuretic peptide (BNP) values (pg/ml) for different mortality causes. In this graph, there were two patients who died of renal causes. Their BNP levels were 1,300 and 805. *p = 0.005 when comparing using BNP between the people who died due to all causes and who survived in the non-referred group; p < 0.001 when comparing using BNP between the people who died due to all causes and who survived in the referred group. Boxes show 25th and 75th percentile with medians given; whiskers show 10th and 90th percentiles.
|
|
View larger version (25K):
[in a new window]
|
Figure 2 Area under receiver-operating characteristic curve (AUC) values for B-natriuretic peptide in predicting death (all-cause including cardiac death) in study groups with and without referral.
|
|
View larger version (25K):
[in a new window]
|
Figure 3 Kaplan-Meier survival curves of the patients who died of all causes (including the cardiac death) with B-natriuretic peptide (BNP) values <120 and  120 pg/ml in the patient groups without referral and with referral.
|
|
|
