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J Am Coll Cardiol, 2004; 44:520-527, doi:10.1016/j.jacc.2004.02.061
© 2004 by the American College of Cardiology Foundation
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Intracoronary brachytherapy after stenting de novo lesions in diabetic patients

Results of a randomized intravascular ultrasound study

Manel Sabaté, MD*,*, Gela Pimentel, MD*, Carlos Prieto, BSc*, JoséMaría Corral, MD*, Camino Bañuelos, MD*, Dominick J. Angiolillo, MD*, Fernando Alfonso, MD*, Rosana Hernández-Antolín, MD*, Javier Escaned, MD*, Panayotis Fantidis, MD*, Cristina Fernández, MD*, Antonio Fernández-Ortiz, MD*, Raúl Moreno, MD* and Carlos Macaya, MD*

* San Carlos University Hospital, Madrid, Spain



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  		Figure 1 Cross-sectional (A and A') and longitudinal (B and B') intravascular ultrasound images of a coronary segment immediately after treatment and at follow-up. Luminal, plaque, and total vessel function curves are represented in the bottom charts (C and C'). In this example, a marked increment of intra-stent neointimal hyperplasia is shown.

 


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  		Figure 2 Change in total vessel volume (TVV), plaque volume (PV), and luminal volume (LV) at the stented segment from post-treatment to follow-up between groups. Open bars = control group; shaded bars = brachytherapy group.

 


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  		Figure 3 Absolute reduction in restenosis rates in the four prespecified coronary segments between groups. Open bars = control group; shaded bars = brachytherapy group.

 


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  		Figure 4 Cumulative frequency distribution curves of MLD between groups at the target segment. By comparison, using the Student t test, the mean MLD at follow-up (F/U) became significant between groups (p > 0.0001).

 


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  		Figure 5 Cumulative frequency distribution curves of minimal luminal diameter between groups at the vessel segment. By comparison, using the Student t test, the mean minimal luminal diameter at follow-up (F/U) was no longer significant between groups.

 




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Copyright © 2004 by the American College of Cardiology Foundation.