Plasma level of oxidized low-density lipoprotein is an independent determinant of coronary macrovasomotor and microvasomotor responses induced by bradykinin
Tetsuya Matsumoto, MD*,*,
Hiroyuki Takashima, MD*,
Naoto Ohira, MD*,
Yasuhiro Tarutani, MD*,
Yo Yasuda, MD*,
Tetsunobu Yamane, MD*,
Shinro Matsuo, MD* and
Minoru Horie, MD*
* Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga, Japan
View larger version (23K):
[in a new window]
|
Figure 1 Effects of diabetes mellitus (DM) and body mass index (BMI) on plasma levels of oxidized low-density lipoprotein (LDL). *p = 0.0002 versus the non-diabetic subjects. Values represent mean ± SEM. Open circles represent non-diabetic subjects; closed circles represent diabetic subjects.
|
|
View larger version (28K):
[in a new window]
|
Figure 2 Relationship between plasma oxidized low-density lipoprotein (oxLDL) levels and coronary vasomotor responses to bradykinin (2.0 µg/min).
|
|
View larger version (28K):
[in a new window]
|
Figure 3 Relationship between plasma low-density lipoprotein (LDL) cholesterol levels and coronary vasomotor responses to bradykinin (2.0 µg/min).
|
|
|
