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The decrease of plaque volume during percutaneous coronary intervention has a negative impact on coronary flow in acute myocardial infarction

A major role of percutaneous coronary intervention-induced embolization

Hiroshi Sato, MD^*,*, Hidetaka Iida, MD^*, Atsushi Tanaka, MD, Hidemasa Tanaka, MD^*, Shinichi Shimodouzono, MD^*, Eiji Uchida, MD^*, Takahiko Kawarabayashi, MD and Junichi Yoshikawa, MD

^* Tsukazaki Memorial Hospital, Himeji, Japan
Baba Memorial Hospital, Sakai, Japan
Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan

View larger version (15K): [in a new window]   Figure 1 The difference in PV between patients with inadequate reflow and reflow. The PV was significantly larger in patients with inadequate reflow than in those with reflow (49.4 ± 18.9 vs. 31.7 ± 15.5 mm3, p = 0.0010). PV = plaque volume.

View larger version (18K): [in a new window]   Figure 2 The relationship between PV during percutaneous coronary intervention (PCI) and corrected TIMI frame count (CTFC) after PCI. In 57 patients with TIMI flow grade 2 or 3, PV significantly correlated with CTFC after PCI (r = 0.415, p = 0.0012). PV = plaque volume.

View larger version (18K): [in a new window]   Figure 3 The changes of plaque volume obtained in the stented segments and distal and proximal reference segments.